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Gene Information

Gene symbol: AXPC1

Gene name: ataxia, posterior column 1, with retinitis pigmentosa

HGNC ID: 906

Related Genes

#	Gene Symbol	Number of hits
1	ICAM1	1 hits
2	INS	1 hits
3	LRP5	1 hits
4	MMP9	1 hits
5	SLC2A4	1 hits

Related Sentences

#	PMID	Sentence
1	3053948	We studied the ability of bovine insulin, porcine insulin, and human insulin ICs to stimulate the procoagulant activity (PCA) of human blood monocytes (HBMs) and human umbilical vein endothelium (HUVE) in vitro.
2	3053948	For four different antibodies, the ratios of PCA (expressed by HBMs exposed to ICs or to antibodies alone and normalized for cell numbers) to activity expressed by tissue culture medium were as follows: beef insulin ICs, 2.55 +/- 0.41; por insulin ICs, 1.47 +/- 0.16; human insulin ICs, 1.28 +/- 0.19; and antibody, 1.28 +/- 0.32.
3	3053948	For a sixth antibody, HBMs could express PCA when stimulated with antibody of a relatively low binding capacity (0.35 ng bovine insulin per microgram of antibody) only in the presence of lymphocytes.
4	3053948	These observations raise the possibility that insulin ICs, that is, beef insulin ICs, may generate increased PCA and thereby contribute to the vascular complications of diabetes mellitus.
5	17505560	PCA and PLS analysis revealed that high values of MMP-9 and low values of ICAM-1 were associated with high radical production whereas MCP-1 and oxLDL were not correlated to radical production.
6	21788573	C3G and PCA increased adipocyte glucose uptake (P < 0.05) and GLUT4 membrane translocation (P < 0.01).
7	21788573	Our study provides evidence that C3G and PCA might exert insulin-like activities by PPAR? activation, evidencing a causal relationship between this transcription factor and adiponectin and GLUT4 upregulation.