- About
- Home
- Introduction
- Statistics
- Programs
- Dignet
- Gene
- GenePair
- Help & Docs
- Documents
- Help
- FAQs
- Links
- Acknowledge
- Disclaimer
- Contact Us
Gene Information
Gene symbol: BBC3
Gene name: BCL2 binding component 3
HGNC ID: 17868
Synonyms: JFY1, PUMA
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | BCL2L1 | 1 hits |
| 2 | IFNG | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 20421300 | Here, we demonstrate that the proinflammatory cytokine interleukin-1beta, combined with interferon-gamma, induces the expression of the Bcl-2 homology 3 (BH3)-only activator PUMA (p53 up-regulated modulator of apoptosis) in beta-cells. |
| 2 | 20421300 | The antiapoptotic Bcl-XL protein is localized mainly at the mitochondria of the beta-cells and antagonizes PUMA action, but Bcl-XL is inactivated by the BH3-only sensitizer DP5/Hrk in cytokine-exposed beta-cells. |