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Gene Information
Gene symbol: BEST1
Gene name: bestrophin 1
HGNC ID: 12703
Synonyms: BMD, BEST
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ACE | 1 hits |
| 2 | ADIPOQ | 1 hits |
| 3 | AGT | 1 hits |
| 4 | EDN1 | 1 hits |
| 5 | INSR | 1 hits |
| 6 | PPARG | 1 hits |
| 7 | REN | 1 hits |
| 8 | TGFB1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 15939809 | The present study demonstrates that AT2R activation and certain ARBs induce adiponectin in adipocytes, which was associated with an improvement of parameters of insulin sensitivity in vivo. |
| 2 | 15939809 | ARB-induced adiponectin stimulation is likely to be mediated via PPARgamma activation involving a post-transcriptional mechanism. |
| 3 | 16290123 | However, by analysis segregated with ACE gene polymorphism, ARB significantly decreased transforming growth factor-beta1 (TGF-beta) compared to ACEI in patients with the I/I genotype but not in patients with the D/I+D/D genotype. |
| 4 | 16290123 | We suggest that in I/I patients, TGF-beta was reduced by ARB via effects on (ATII) type 2 receptors (AT2). |
| 5 | 16290123 | In our experiments, the effect of ARB on TGF-beta reduction was only detected by segregation of ACE genotypes. |
| 6 | 17487263 | This project assesses the treatment role with insulin and (or) angiotensin II receptor subtype-1 (AT1-R) blocker (ARB) on insulin receptor and endothelin-1 receptor subtype (ETA-R and ETB-R) regulation in rat hearts suffering from insulin-dependent diabetes mellitus (IDDM). |
| 7 | 18829990 | In the present study, we determined whether hyperglycemia activates the cardiac intracellular renin-Ang system (RAS) in vivo and whether ARBs, ACE, or renin inhibitors block synthesis and effects of intracellular Ang II (iAng II). |
| 8 | 18829990 | Diabetic rats were treated with insulin, candesartan (ARB), benazepril (ACE inhibitor), or aliskiren (renin inhibitor). |
| 9 | 18829990 | Renin inhibition has a more pronounced effect than ARBs and ACE inhibitors on these diabetes complications and may be clinically more efficacious. |
| 10 | 19665690 | Because angiotensin II (Ang II) inhibits sensory neuron activation by interacting with Ang II type 1 (AT(1)) receptors, it is possible that AT(1) receptor blockers (ARBs) increase IGF-I production in SHRs. |
| 11 | 19453256 | We evaluated sex differences in the prospective association between adiponectin with BMD, bone loss, and fractures. |
| 12 | 21143168 | In this paper, I describe the effects of ARBs on adiponectin, blood pressure, and fatty liver. |
| 13 | 21143168 | Several clinical studies have reported that ARBs elevate adiponectin. |
| 14 | 20948237 | These data suggest that the addition of 1,25(OH)(2)D(3) to therapy with ARB further reduced proteinuria by suppressing the compensatory increase in renin expression in type 2 diabetic nephropathy. |