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Gene Information

Gene symbol: BGN

Gene name: biglycan

HGNC ID: 1044

Synonyms: DSPG1, SLRR1A

Related Genes

# Gene Symbol Number of hits
1 ACE 1 hits
2 COL1A1 1 hits
3 CXCL13 1 hits
4 FMOD 1 hits

Related Sentences

# PMID Sentence
1 11259366 Biglycan was expressed by glomerular endothelial cells and, together with fibromodulin, by distal tubular cells and in collecting ducts.
2 21084753 Here, we have shown that the proteoglycan biglycan triggers CXCL13 expression via TLR2/4 in macrophages and dendritic cells.
3 21084753 Importantly, biglycan also triggered CXCL13 expression and B cell infiltration in the healthy kidney.
4 21084753 Collectively, our results describe what we believe to be a novel mechanism for the regulation of CXCL13 by biglycan, a host-derived ligand for TLR2/4.
5 18348167 By affinity coelectrophoresis (ACE), we found reduced affinities of heparin and KSPGs for glycated but not normal collagen, whereas the dermatan sulfate (DS)PGs decorin and biglycan bound similarly to both, and that the affinity of heparin for normal collagen decreased with increasing pH.