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Gene Information
Gene symbol: C11orf2
Gene name: chromosome 11 open reading frame2
HGNC ID: 1172
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | AGT | 1 hits |
| 2 | CDH5 | 1 hits |
| 3 | MAPK1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 11289054 | In this study, we investigated the effect of angiotensin II (AII) on Ang1 and Ang2 expression in cultured bovine retinal endothelial cells (BRECs). |
| 2 | 11289054 | Protein kinase C (PKC) inhibitor completely inhibited AII-induced Ang2 expression, and the mitogen-activated protein kinase (MAPK) inhibitor also inhibited it by 69.4+/-15.6%. |
| 3 | 11289054 | These data suggest that AII stimulates Ang2 expression through AT1 receptor-mediated PKC and MAPK pathways in BREC, and AII may play a novel role in retinal neovascularization. |
| 4 | 21310918 | Ang-2 increased HREC monolayer permeability that was associated with a decrease in VE-cadherin and a change in monolayer morphology. |
| 5 | 21310918 | Increased Ang-2 alters VE-cadherin function, leading to increased vascular permeability. |