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Gene Information

Gene symbol: C12orf5

Gene name: chromosome 12 open reading frame 5

HGNC ID: 1185

Synonyms: TIGAR

Related Genes

# Gene Symbol Number of hits
1 SCO2 1 hits
2 TP53 1 hits

Related Sentences

# PMID Sentence
1 21185935 In vitro data indicate that cellular levels of reactive oxygen species depend on the expression and activity of p53, which plays a key role in energy metabolism and as a crucial transcription factor for SCO cytochrome oxidase deficient homolog 2 (SCO2) and tumor p53-induced glycolysis and apoptosis regulator (TIGAR), which regulate mitochondrial respiration and glycolysis in cells.
2 21185935 Exercise training decreased p53 protein levels and TIGAR expression in skeletal muscle (P<0.05), but SCO2 expression was unchanged.