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Gene Information

Gene symbol: C4A

Gene name: complement component 4A (Rodgers blood group)

HGNC ID: 1323

Synonyms: CPAMD2, C4S, CO4, C4, C4A3, C4A2, C4A4, C4A6, C4B, RG

Related Genes

# Gene Symbol Number of hits
1 C5AR1 1 hits
2 IDDM2 1 hits

Related Sentences

# PMID Sentence
1 6955994 The silent allele C4s degree was particularly associated with early diagnosed IDDM (86.7% in patients with age at onset under 20 years vs 57.1% in other patients, P less than 0.02).
2 3907907 C4a levels were also elevated in 2 of these patients (P less than 0.02), but C5a levels, although higher than normal, were not significantly increased.
3 2642174 C4 phenotype frequencies showed a significant increase of the C4AQ0 (rr = 2.13) and C4A4 (rr = 2.91) phenotypes for the Caucasian IDDM patients as compared to controls, but the frequency of homozygous null C4A was not significantly increased.
4 2642174 In addition significant negative associations of IDDM with C4A3 and C4A6 phenotypes and no association with any C4B phenotype were observed in our Caucasian patient population.
5 2642174 The data support a possible association of IDDM with the C4A2 (rr = 5.86) and C4B2 (rr = 5.26) phenotypes.