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Gene Information
Gene symbol: CALR
Gene name: calreticulin
HGNC ID: 1455
Synonyms: RO, SSA, cC1qR, CRT, FLJ26680
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ATF4 | 1 hits |
| 2 | ATF6 | 1 hits |
| 3 | CANX | 1 hits |
| 4 | EIF2AK3 | 1 hits |
| 5 | HSPA5 | 1 hits |
| 6 | S100A11 | 1 hits |
| 7 | SLC2A1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 16210549 | Using RNA mobility shift, UV cross-linking, and in vitro degradation assays, followed by mass-spectrometric analysis, we identified calreticulin as a specific destabilizing trans-acting factor that binds to a 10-nucleotide cis-acting element (CAE(2181-2190)) in the 3'-untranslated region of GLUT-1 mRNA. |
| 2 | 17458497 | Of special interest among the differentially expressed proteins are those involved in protein folding (Hsp60, protein disulfide isomerase, calreticulin), Ca(2+) binding (calgizzarin, calcyclin and annexin I) and metabolism or signalling (pyruvate kinase, alpha enolase and protein kinase C inhibitor 1). |
| 3 | 21475143 | Examined were the effects of intravenously infused glucose and/or lipids on proximal ER stress sensor activation (PERK, eIF2-?, ATF4, Xbox protein 1 (XBP1s)), unfolded protein response (UPR) proteins (GRP78, calnexin, calreticulin, protein disulphide isomerase (PDI), stress kinases (JNK, p38 MAPK) and insulin signaling (insulin/receptor substrate (IRS) 1/2 associated phosphoinositol-3-kinase (PI3K)) in rat liver. |
| 4 | 21475143 | Glucose and/or lipid infusions, ranging from 23.8 to 69.5 kJ/4 h (equivalent to between ~17% and ~50% of normal daily energy intake), activated the proximal ER stress sensor PERK and ATF6 increased the protein abundance of calnexin, calreticulin and PDI and increased two GRP78 isoforms. |