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Gene Information
Gene symbol: CBR1
Gene name: carbonyl reductase 1
HGNC ID: 1548
Synonyms: SDR21C1
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ABCA1 | 1 hits |
| 2 | ACACA | 1 hits |
| 3 | FAS | 1 hits |
| 4 | INS | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 20728534 | Under both conditions, knockdown of CBR1 by specific siRNA increased ?-cell apoptosis, expression of lipogenic enzymes (such as ACC, FAS, and ABCA1), intracellular lipid accumulation, oxidative stress, ER stress, and nuclear SREBP1c, but decreased glucose-stimulated insulin secretion. |
| 2 | 20728534 | The antioxidants N-acetyl-l-cysteine and Tiron, as well as the FAS inhibitor cerulenin, reversed the effects of CBR1 knockdown. |