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Gene Information

Gene symbol: CCL5

Gene name: chemokine (C-C motif) ligand 5

HGNC ID: 10632

Synonyms: RANTES, SISd, TCP228, MGC17164

Related Genes

#	Gene Symbol	Number of hits
1	CCL2	1 hits
2	CCL21	1 hits
3	CCL3	1 hits
4	CCR1	1 hits
5	CCR5	1 hits
6	CD8A	1 hits
7	IL8	1 hits
8	IL8RA	1 hits
9	INS	1 hits
10	MS	1 hits
11	NFKB1	1 hits
12	RELA	1 hits
13	SPP1	1 hits

Related Sentences

#	PMID	Sentence
1	12947308	Ribonuclease protection assay was used to determine gene expression for cell markers F4/80 (macrophages), CD8 (type I T cells), CD4 (type II T cells), and CD 19 (natural killer cells), and for chemokines IP-10, MIP-1alpha, MIP-1beta, MCP-1, and RANTES.
2	14510696	Transduced syngeneic transplanted islets showed significantly enhanced expression of multiple chemokines and receptors, including monocyte chemoattractant protein-1 (MCP-1), CC chemokine receptor 2 (CCR2) and regulated upon activation, normal T cell expressed and secreted (RANTES), compared with untransduced islet grafts.
3	15280531	Nuclear factor-kappaB (NF-kappaB) regulates genes involved in renal disease progression, such as the chemokines monocyte chemoattractant protein-1 (MCP-1) and RANTES.
4	15718270	Expression of all four RANTES receptor mRNAs in osteoblast is in contrast to the reports of expression of CCR1 being the only RANTES receptor expressed by osteoclasts.
5	15943778	Transcript levels of CXCR3 and its ligands, interferon-inducible protein 10 (IP-10) and monokine induced by IFN-gamma (Mig), significantly increased between early and late time points together with expression of MIP-1alpha, regulated on activation normal T expressed and secreted protein (RANTES) and MCP-1.
6	16306328	Systemic concentrations of RANTES were higher in individuals with IGT or type 2 diabetes than in control subjects, whereas IL-8 levels were elevated in type 2 diabetic patients only (P < 0.001 for all comparisons).
7	16855620	RANTES is genetically associated with asthma, sarcoidosis and multiple sclerosis.
8	20872723	Quantitative RT-PCR was used to measure viral RNA and mRNA of cytokines interferon (IFN)-?, IFN-?, IFN-?, tumor necrosis factor (TNF)-?, and chemokine (C-X-C motif) ligand 10 (CXCL10), chemokine (C-C motif) ligand 2 (CCL2), and chemokine (C-C motif) ligand 5 (CCL5) in infected INS-1 cells.
9	20953353	TWEAK promotes the secretion of MCP-1 and RANTES through NF-kappaB RelA-containing complexes and upregulates CCl21 and CCL19 expression through NF-kappaB inducing kinase (NIK-) dependent RelB/NF-kappaB2 complexes.
10	15918915	Gene expression of ICAM-1, VCAM-1 and RANTES was unaltered whereas Osteopontin and MCP-1 were induced by hypertension.
11	20200310	In view of the previously described anti-inflammatory effects of insulin, we investigated the potential suppressive effect of insulin on plasma concentrations and expression of the chemokines, monocyte chemoattractant protein-1 (MCP-1) and regulated on activation normal T-cell expressed and secreted (RANTES) and their receptors, chemokine receptor (CCR)-2 and CCR-5, in mononuclear cells (MNCs).
12	20200310	Insulin infusion significantly suppressed the plasma concentrations of MCP-1, eotaxin, and RANTES and the expression of RANTES, macrophage inflammatory protein (MIP)-1beta, CCR-2, and CCR-5 in MNCs at 2 and 4 h.
13	20200310	A low-dose infusion of insulin suppresses the plasma concentration of key chemokines, MCP-1, and RANTES, and the expression of their respective receptors, CCR-2 and CCR-5, in MNCs.
14	20200310	Insulin also suppresses the expression of RANTES and MIP-1beta in MNCs.
15	21890375	In conclusion these data demonstrate that adiponectin stimulates release of CCL2 to CCL5 in primary human monocytes, and induction in cells of overweight probands is partly impaired.