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Gene Information
Gene symbol: CD44
Gene name: CD44 molecule (Indian blood group)
HGNC ID: 1681
Synonyms: IN, MC56, Pgp1, CD44R, HCELL, CSPG8
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ALB | 1 hits |
| 2 | APOA5 | 1 hits |
| 3 | CD34 | 1 hits |
| 4 | CD8A | 1 hits |
| 5 | COL1A1 | 1 hits |
| 6 | COL4A4 | 1 hits |
| 7 | ITGAL | 1 hits |
| 8 | KDR | 1 hits |
| 9 | KIT | 1 hits |
| 10 | MKI67 | 1 hits |
| 11 | MMP7 | 1 hits |
| 12 | NFKB1 | 1 hits |
| 13 | NOS2A | 1 hits |
| 14 | PDX1 | 1 hits |
| 15 | TNF | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 2948855 | Treatment of human glomerular basement membrane (GBM) with 4 M guanidine HCl resulted in a preferential extraction of noncollagenous components including laminin, fibronectin, entactin, and heparan sulfate proteoglycan, whereas effective solubilization of type IV collagen required exposure to denaturing solvents in the presence of reducing agents. |
| 2 | 2972877 | An increased synthesis of type IV collagen with concomitant decrease of heparan sulfate proteoglycan may lead to alteration of the charge selective barrier and consequently to increased permeability of the glomerular BM. |
| 3 | 2482599 | While the enlarged mesangial matrix in diffuse glomerulosclerosis showed an increased staining reaction for the basement membrane components collagen IV and V, laminin and fibronectin, the staining pattern of the basement membrane associated heparan sulfate proteoglycan (HSPG) was markedly reduced. |
| 4 | 16424185 | These alloreactive CD8+ T cells 1) expressed the proliferation marker Ki-67, 2) up-regulated CD44, and 3) failed to undergo apoptosis. |
| 5 | 17460896 | The cells expressed CD29, CD44, and CD166, but did not express CD11a, CD14, CD34, CD45, CD90, CD105, and CD117. |
| 6 | 17495607 | An indirect triacylglycerol-modulating effect of apoA-V has been attributed to heparan sulfate proteoglycan binding, as confirmed by structural studies. |
| 7 | 20713153 | CD44 stimulation activates the protein kinase C (PKC) family which in turn activates the transcriptional nuclear factor kappa B (NF-?B) responsible for the expression of the inflammation mediators such as tumor necrosis factor alpha (TNF-?), interleukin-6 (IL-6), interleukin-18 (IL-18), inducible nitric oxide synthase (iNOS), and matrix metalloproteinases (MMPs). |
| 8 | 20713153 | Chronic daily administration of high-molecular mass HA for 2 weeks significantly reduced CD44, PKC(?I), PKC(?II), and PKC? gene expression and the related protein production in kidney tissue and TNF-?, IL-6, IL-18, MMP-7, and iNOS expression and levels also decreased. |
| 9 | 21493893 | Flow cytometry analyses of these cultured cells at passage 4 showed expression of typical MSC markers such as CD44 and CD29, but not hematopoietic markers such as c-kit, flk1, and CD34. |
| 10 | 21606656 | Inflammatory gene expression correlated with albuminuria and C3 and CD44 increased in tubules that accumulated albumin. |
| 11 | 10222028 | In support of this interpretation, we found that the accessory molecules CD4, CD44, and B7-1 (all of which are involved in T cell co-stimulation) were cleaved by Phlogenzym, while CD3 and MHC class II molecules (which are involved in the recognition of antigens by T cells) and LFA-1 were unaffected. |
| 12 | 21612404 | Here, we show that PDX-1 plays an important role in the induction of CD44+/CD105+ human amniotic fluid cells (HuAFCs) into functional pancreatic ?-cell-like cells in vitro. |