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Gene Information
Gene symbol: CD59
Gene name: CD59 molecule, complement regulatory protein
HGNC ID: 1689
Synonyms: 16.3A5, EJ16, EJ30, EL32, G344, p18-20
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD46 | 1 hits |
| 2 | CR1 | 1 hits |
| 3 | INS | 1 hits |
| 4 | PLCB1 | 1 hits |
| 5 | SORD | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 3836706 | Erythrocyte sorbitol dehydrogenase activity was significantly lower for 34 diabetic patients (mean +/- SD: 0.219 +/- 0.085 U min-1 g Hb-1) than for 27 normal blood donors (0.34 +/- 0.094 U min-1 g Hb-1). |
| 2 | 8384133 | The tyrosine kinase activity of insulin receptors isolated from the control and NIDDM fibroblasts was similar (basal, 135 +/- 30 vs. 149 +/- 33; submaximal, 153 +/- 28 vs. 155 +/- 30; and maximal insulin, 191 +/- 45 vs. 213 +/- 48 dpm.mg protein-1 x min-1). |
| 3 | 10990082 | High concentrations of glucose decreased the expression of CD59 and CD55 by endothelial cells in a time-dependent and glucose concentration-dependent manner without affecting CD46 expression. |
| 4 | 10990082 | We speculate that hyperglycaemia could directly contribute to a loss of CD59 and CD55 molecules through a calcium-dependent phosphoinositol-specific phospholipase C activation and subsequent regulation of cell wall expression of GPI-anchored proteins. |
| 5 | 16837818 | The levels of decay accelerating factor (DAF) and CD59 on erythrocytes (E) were also determined to ascertain whether the loss of CR1 is a specific phenomenon or other complement regulatory proteins are also affected. |