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Gene Information
Gene symbol: CD72
Gene name: CD72 molecule
HGNC ID: 1696
Synonyms: LYB2, CD72b
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | BLK | 1 hits |
| 2 | BTK | 1 hits |
| 3 | CD19 | 1 hits |
| 4 | GRB2 | 1 hits |
| 5 | PTPN6 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 16290205 | Whereas NON, C57BL/6 and AKR mice expressed CD72 on 98, 94 and 92% of their B-lymphocytes (CD19+ cells), the NOD mice only expressed this regulatory marker on 78% of their B-lymphocytes. |
| 2 | 19067131 | DISCUSSION: CD72 ligation induces a variety of early signaling events such as activation of the Src kinases Blk and Lyn and the non-src kinase Btk leading to activation of the mitogen-activated protein (MAP) kinases, events usually associated with positive signaling. |
| 3 | 19067131 | Thus, CD72 interacts with SHP-1, an SH2-domain containing protein tyrosine phosphatase, a negative regulator of signaling, and Grb2, an adaptor protein associated with the Ras/MAPK pathway. |
| 4 | 19067131 | Ligation of CD72 also triggered its association with CD19, a positive modulator of B cell receptor signaling. |