Ignet

Gene symbol: CHEK1

Gene name: checkpoint kinase 1

HGNC ID: 1925

Synonyms: CHK1

Related Genes

Related Sentences

#	PMID	Sentence
1	20473325	Simultaneous deletion of one copy of p53 failed to rescue the developmental defects; however, it synergistically induced mammary tumor formation in Chk1(+/-);MMTV-Cre animals with a median time to tumor latency of about 10 months.
2	20473325	Chk1 deficiency caused a preponderance of abnormalities, including prolongation, multipolarity, misalignment, mitotic catastrophe and loss of spindle checkpoint, that are accompanied by reduced expression of several cell cycle regulators, including Mad2.