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Gene Information
Gene symbol: CHGA
Gene name: chromogranin A (parathyroid secretory protein 1)
HGNC ID: 1929
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | AKT1 | 1 hits |
| 2 | ENO2 | 1 hits |
| 3 | GPC3 | 1 hits |
| 4 | IGF1 | 1 hits |
| 5 | MAPK1 | 1 hits |
| 6 | PCSK1 | 1 hits |
| 7 | PDAP1 | 1 hits |
| 8 | PDCD4 | 1 hits |
| 9 | ST8SIA4 | 1 hits |
| 10 | SYP | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 8096340 | Adrenal chromaffin cells exhibited strong immunoreactivity for CGA but lacked CST and PST immunoreactivities. |
| 2 | 12584991 | The expression of chromogranin A, S-100 protein and ACTH was examined using the PAP method, while neuronspecific enolase (NSE), synaptophysin and neurofilament were examined by the APAAP method with appropriate antibodies (DAKO). |
| 3 | 16424676 | IGF-1 potently induced CgA secretion. |
| 4 | 18549351 | Using this cell line, we found that suppression of Pdcd4 resulted in an increased release of CgA (chromogranin A) and Sg II (secretogranin II), and was accompanied by an up-regulation of intracellular PC1 (proprotein convertase 1/3). |
| 5 | 18549351 | The enhanced secretion of CgA and Sg II seemed to be mediated by an activation of protein kinase Akt via PI3K (phosphoinositide 3-kinase). |
| 6 | 18549351 | Neither the PKC (protein kinase C) signal transduction cascade nor the MAPK (mitogen-activated protein kinase) pathway seemed to play a role in the regulation of CgA and Sg II secretion by Pdcd4. |
| 7 | 18549351 | Our results are of particular interest, as we observed that pioglitazone, an oral medication used in the treatment of Type 2 diabetes, decreased Pdcd4 levels, activated Akt, increased CgA and Sg II secretion and augmented PC1 protein in Bon-1 cells. |
| 8 | 21084851 | These data suggest that SGB may by regulated at a post-transcriptional level with no evidence to indicate that CgA regulates SGB in the cell line HUH7-ins. |