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Gene Information

Gene symbol: CLCN5

Gene name: chloride channel, voltage-sensitive 5

HGNC ID: 2023

Synonyms: DENTS, XLRH, hClC-K2, hCIC-K2, CLC5, XRN, ClC-5

Related Genes

# Gene Symbol Number of hits
1 CUBN 1 hits
2 IMMT 1 hits
3 KIF3B 1 hits
4 LRP2 1 hits

Related Sentences

# PMID Sentence
1 19940036 Loss of CLC-5 function alters receptor-mediated endocytosis and trafficking of megalin and cubilin, although the underlying mechanisms remain to be elucidated.
2 19940036 Here, we report that CLC-5 interacts with kinesin family member 3B (KIF3B), a heterotrimeric motor protein that facilitates fast anterograde translocation of membranous organelles.
3 19940036 KIF3B overexpression and underexpression, using siRNA, had reciprocal effects on whole cell chloride current amplitudes, CLC-5 cell surface expression, and endocytosis of albumin and transferrin.