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Gene Information
Gene symbol: CLCN5
Gene name: chloride channel, voltage-sensitive 5
HGNC ID: 2023
Synonyms: DENTS, XLRH, hClC-K2, hCIC-K2, CLC5, XRN, ClC-5
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
19940036
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Loss of CLC-5 function alters receptor-mediated endocytosis and trafficking of megalin and cubilin, although the underlying mechanisms remain to be elucidated.
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2 |
19940036
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Here, we report that CLC-5 interacts with kinesin family member 3B (KIF3B), a heterotrimeric motor protein that facilitates fast anterograde translocation of membranous organelles.
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3 |
19940036
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KIF3B overexpression and underexpression, using siRNA, had reciprocal effects on whole cell chloride current amplitudes, CLC-5 cell surface expression, and endocytosis of albumin and transferrin.
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