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Gene Information
Gene symbol: CLDN5
Gene name: claudin 5
HGNC ID: 2047
Synonyms: CPETRL1, BEC1
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ATF2 | 1 hits |
| 2 | SOD3 | 1 hits |
| 3 | TJP1 | 1 hits |
| 4 | VEGFA | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 20627932 | Diabetes also decreased occludin and claudin-5 levels and altered the distribution of ZO-1 and occludin in retinal vessels. |
| 2 | 21502138 | Furthermore, the CES-2-like basic region leucine-zipper (bZip) transcription factor ATF-2, an upstream modulator of the core apoptotic cell death pathway, is able to directly regulate the expression of at least two key autophagy-related genes, bec-1/ATG6 and lgg-1/ATG8. |
| 3 | 21409414 | AGEs reduced the production of claudin-5 in PnMECs by increasing autocrine signalling through vascular endothelial growth factor (VEGF) secreted by the PnMECs themselves. |
| 4 | 21736484 | Our observations suggest that ER stress leads to the down-regulation of claudin-5 among tight junction proteins and may induce the elevation of endothelial permeability and leakage of EC-SOD into the vitreous body. |