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Gene Information
Gene symbol: CLOCK
Gene name: clock circadian regulator
HGNC ID: 2082
Synonyms: KIAA0334, KAT13D, bHLHe8
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | NAMPT | 1 hits |
| 2 | PPARA | 1 hits |
| 3 | PRKAA2 | 1 hits |
| 4 | SERPINE1 | 1 hits |
| 5 | SIRT1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 21733059 | AMPK activity, NAMPT expression and SIRT1 expression were decreased in WAT of db/db and HFD mice, in association with suppressed expression of the core circadian components CLOCK and BMAL1. |
| 2 | 15500444 | Using wild-type and Clock-deficient fibroblasts derived from homozygous Clock mutant mice, we showed that the circadian expression of PPARalpha mRNA is regulated by the peripheral oscillators in a CLOCK-dependent manner. |
| 3 | 15500444 | These results suggested that CLOCK plays an important role in lipid homoeostasis by regulating the transcription of a key protein, PPARalpha. |
| 4 | 15950223 | Our results suggested that the circadian clock component, CLOCK, is involved in the diabetes-induced circadian augmentation of PAI-1 expression in the mouse heart. |
| 5 | 19387897 | The circadian expression of PAI-1 gene is thought to be directly regulated by the circadian clock proteins such as CLOCK and BMAL1/BMAL2 which drive the endogenous biological clock. |