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Gene Information

Gene symbol: CNBP

Gene name: CCHC-type zinc finger, nucleic acid binding protein

HGNC ID: 13164

Synonyms: RNF163, ZCCHC22, CNBP1

Related Genes

#	Gene Symbol	Number of hits
1	ABCA1	1 hits
2	ABCA4	1 hits
3	ADIPOQ	1 hits
4	CYP1A1	1 hits
5	CYP2B6	1 hits
6	G6PD	1 hits
7	GPAM	1 hits
8	IL1B	1 hits
9	IL6	1 hits
10	INS	1 hits
11	REN	1 hits
12	RETN	1 hits
13	TIMP2	1 hits
14	TNF	1 hits

Related Sentences

#	PMID	Sentence
1	10861205	Insulin stimulates the transcription of the sterol regulatory- element binding protein (SREBP) 1/ADD1 gene in liver.
2	12923232	The LXR ligand T0901317 elevates ATP binding cassette transporter A1 (ABCA1) and HDL levels in animal models and induces moderate lipogenesis through upregulation of sterol regulatory element binding protein 1c (SREBP1c).
3	16313475	Resistin, a peptide hormone produced by adipocytes, has been associated with diabetes mellitus type 2 (DM-2) in some rodent models.
4	16313475	Some, but not all studies have found associations between polymorphisms in the resistin gene with DM-2.
5	16313475	Recently a 3'-untranslated region +62G-->A polymorphism of the resistin gene has been associated with decreased risk for DM-2 and for hypertension in diabetics in a Chinese population.
6	16313475	In conclusion, the present data suggest that in a German Caucasian population the +62G-->A polymorphism of the resistin gene is associated with hypertension but not with DM-2.
7	16429400	Sterol regulatory element binding protein 1 (SREBP-1) transcription factors play a key role in energy homeostasis by regulating genes involved in both carbohydrate and lipid metabolism, and in adipocyte differentiation.
8	16429400	Mutations in the sterol regulatory element binding protein gene (SREBF)-1 may contribute to insulin resistance states.
9	17508916	Hyperglycemia, elevated circulating fatty acids, inadequate local activation of renin angiotensin system, and chronic low grade inflammation are conditions that coexist in the CMS and DM2 that turn out to be deleterious for the beta-cell functioning and existance.
10	17622585	In this study, we provide evidence in rats that low-dose alcohol intake (4 g/kg x d) enhances hepatic insulin signaling by suppressing p55gamma (a phosphatidylinositol 3-kinase regulatory subunit isoform) at the posttranscriptional level, leading to the increased association of the phosphatidylinositol 3-kinase catalytic subunit (p110) with insulin receptor substrate-1 (P < 0.05) and subsequent activation of downstream effectors such as Akt, glycogen synthase kinase 3beta, and nuclear sterol regulatory element binding protein (SREBP)-1.
11	17879211	Further, in DM2 patients, TIMP-2 was decreased when compared with CRF alone (219.2 +/- 71.8 vs. 296.8 +/- 58.4 ng/mL).
12	19125180	Resistin mRNA expression is increased in PBMC from DM2 women, together with increased expression of the inflammatory cytokines IL-1beta, TNF-alpha, and IL-6, independent of obesity.
13	19062325	The isoforms of the transcription factor sterol regulatory element binding protein 1 (SREBP-1) are known to stimulate G6PD gene expression, and some polymorphisms in the SREBP-1 gene (SREBF-1) have been described only in Africans.
14	20889139	The serum adiponectin levels at baseline had decreased tendency with significant difference between each two groups, while CRP, TNF-?, and IL-6 levels had increased tendency with significant difference between each two groups among NC, IGT, DM1 and DM2 groups (all P<0.01).
15	20200319	In ob/ob mice, sterol regulatory element binding protein 1 (SREBP1) mediates the induction of steatosis by upregulating target genes, including glycerol-3-phosphate acyltransferase-1 (Gpat1), which catalyzes the first and committed step in the pathway of glycerolipid synthesis.
16	21568932	Patients with DM2 show an improvement of plasma lipoprotein profile and glucose tolerance together with increase in liver phospholipid (PL) and cytochrome (CYP) P450.