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Gene Information
Gene symbol: COL18A1
Gene name: collagen, type XVIII, alpha 1
HGNC ID: 2195
Synonyms: KS, KNO1
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ANGPT2 | 1 hits |
| 2 | COL1A1 | 1 hits |
| 3 | HBB | 1 hits |
| 4 | IL6 | 1 hits |
| 5 | INS | 1 hits |
| 6 | KDR | 1 hits |
| 7 | PLG | 1 hits |
| 8 | VEGFA | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 16186390 | Here, we examine the effect of endostatin peptide, a potent inhibitor of angiogenesis derived from type XVIII collagen, in preventing progression in the type 1 diabetic nephropathy mouse model. |
| 2 | 16186390 | Glomerular mesangial matrix expansion, the increase of glomerular type IV collagen, endothelial area (CD31(+)), and F4/80(+) monocyte/macrophage accumulation were significantly inhibited by endostatin peptide. |
| 3 | 16186390 | Increase in the renal expression of VEGF-A, flk-1, Ang-2, an antagonist of angiopoietin-1, transforming growth factor-beta1, interleukin-6, and monocyte chemoattractant protein-1 was inhibited by endostatin peptide in diabetic mice. |
| 4 | 16186390 | Endogenous renal levels of endostatin were decreased in endostatin peptide-treated groups in parallel with VEGF-A. |
| 5 | 18056916 | Arterial hypertension (HT) has been reported in all studies involving bevacizumab, an antiangiogenic agent designed to target vascular endothelial growth factor (VEGF). |
| 6 | 18490555 | Skeletal muscle expression of plasminogen and collagen XVIII (precursors of angiostatin and endostatin, respectively) remained similar between nondiabetic and diabetic swine and patients. |
| 7 | 18023664 | Myocardial expression of anti-angiogenic proteins, angiostatin and endostatin, showing a 4.3- and 3.6-fold increase in diabetic animals respectively (both P < .01 vs ND), was markedly reduced in insulin-treated animals (2.3- and 1.8-fold vs ND; both P < .01). |
| 8 | 19074676 | Myocardial endostatin expression correlated strongly with the percentage of hemoglobin A(1c) (r = 0.742, P = 0.0001). |