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Gene Information
Gene symbol: COL1A2
Gene name: collagen, type I, alpha 2
HGNC ID: 2198
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
9795371
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In the diabetic patients, we further determined serum levels of proinsulin, intact parathyroid hormone (PTH), 25-hydroxyvitamin D3, 1,25-dihydroxyvitamin D3 and several biochemical bone markers, including osteocalcin (OSC), bone alkaline phosphatase (B-ALP), carboxy-terminal propeptide of type I procollagen (PICP), and type I collagen cross-linked carboxy-terminal telopeptide (ICTP).
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2 |
20713358
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TGF-? also enhanced protein levels of Tsc-22 (TGF-?-stimulated clone 22) and collagen type I ?-2 (Col1a2) expression in MC through far upstream enhancer E-boxes by interaction of Tsc-22 with an E-box regulator, Tfe3.
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3 |
20713358
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Chromatin immunoprecipitation (ChIP) assays revealed that TGF-? could increase the occupancies of Tsc-22 and Tfe3 on enhancer E-boxes of Col1a2.
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4 |
20713358
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These results demonstrate that post-transcriptional regulation of Tsc-22 mediated through Ybx1, a miR-216a target, plays a key role in TGF-?-induced Col1a2 in MC related to the pathogenesis of diabetic nephropathy.
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5 |
21389977
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Inhibitors of miR-192 decreased the expression of miR-200b/c, Col1a2, Col4a1, and TGF-?1 in mouse mesangial cells, and in mouse kidney cortex.
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