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Gene Information

Gene symbol: CPB2

Gene name: carboxypeptidase B2 (plasma)

HGNC ID: 2300

Synonyms: CPU, PCPB, TAFI

Related Genes

#	Gene Symbol	Number of hits
1	ADIPOQ	1 hits
2	ALB	1 hits
3	APOE	1 hits
4	INS	1 hits
5	MMP2	1 hits
6	MMP9	1 hits
7	PLAT	1 hits
8	SERPINE1	1 hits
9	VEGFA	1 hits

Related Sentences

#	PMID	Sentence
1	2140181	Urinary (CPU) and plasma C peptide values at baseline (CP0) and under stimulation with glucagon were determined in healthy subjects (n = 17) and in insulin-dependent (IDD, n = 45) and non insulin-dependent (NIDD, n = 32) diabetics.
2	16389166	TAFI activity did not significantly correlate with age, albumin excretion, fasting plasma glucose, HbA(1c), D-dimer, and fibrinogen by Spearman rank correlation test.
3	16877877	Thrombin activatable fibrinolysis inhibitor is a carboxypeptidase that cleaves the carboxylic lysine residues on fibrin, thereby abolishing the critical binding site for tPA-plasminogen decreasing plasmin formation.
4	17509067	At baseline, serum HMW adiponectin correlated negatively with plasma TAFI in all patients with Type 2 diabetes (r = -0.367, P = 0.0423).
5	17988229	The renal content of hydroxyproline and the activity of plasmin, MMP-2 and MMP-9 were significantly increased in kidneys with UUO from TAFI-deficient mice compared with those from wild-type mice.
6	19436948	Only TAFI correlated with VEGF in MAU.
7	20723031	Apo-E deficiency alone was not associated with tumors but the lack of TAFI appears to make the mice permissive for tumor formation in ApoE mice.
8	21519232	TAFI was significantly increased in the MAU group, PAI-1 and F1+2 were increased in both groups and t-PA was not elevated in either group compared to controls.
9	21519232	TAFI-mediated inhibition of fibrinolysis in DM2 is regulated independently from PAI-1.