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Gene Information
Gene symbol: CREBBP
Gene name: CREB binding protein
HGNC ID: 2348
Synonyms: RTS, CBP, KAT3A
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | AKT1 | 1 hits |
| 2 | COL1A1 | 1 hits |
| 3 | FOXO4 | 1 hits |
| 4 | IGFBP1 | 1 hits |
| 5 | INS | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 10973497 | A C-terminal deletion mutant of DAF-16 that is nonfunctional in C. elegans fails to bind the KIX domain of CBP, fails to activate transcription through the IGFBP-1.IRE, and inhibits activation of the IGFBP-1 promoter by glucocorticoids. |
| 2 | 10973497 | Although AFX interacts with the KIX domain of CBP, it does not interact with SRC and does not respond to glucocorticoids or insulin. |
| 3 | 15590659 | These data suggest that insulin inhibits glucagon gene transcription by signaling via PI 3-kinase and PKB, with the transcription factor Pax6 and its potential coactivator CBP being critical components of the targeted promoter-specific nucleoprotein complex. |
| 4 | 19450513 | Mice carrying a germline mutation of this CBP phosphorylation site (S436A) demonstrate resistance to the hypoglycemic effect of both insulin and metformin. |
| 5 | 21801741 | The MLD motif, present only in heterodimeric disintegrins, mediates binding of these disintegrins to ?4?1, ?4?7 and ?9?1 integrins, whereas the presence of a KTS or RTS sequence in the active site selectively directs activity of disintegrins to the collagen receptor ?1?1 integrin. |