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Gene Information
Gene symbol: CSH1
Gene name: chorionic somatomammotropin hormone 1 (placental lactogen)
HGNC ID: 2440
Synonyms: hCS-A, CSA, PL, CSMT, FLJ75407
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CDKN1A | 1 hits |
| 2 | CFD | 1 hits |
| 3 | GH1 | 1 hits |
| 4 | IGF1 | 1 hits |
| 5 | INS | 1 hits |
| 6 | TAF9 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 21986512 | Human placental lactogen (hPL) and prolactin increase maternal food intake by induction of central leptin resistance and promote maternal beta-cell expansion and insulin production to defend against the development of gestational diabetes mellitus. |
| 2 | 4700328 | Those patients requiring the largest insulin increment for the control of their diabetes in the pregnancy have placental lactogen levels in the higher range. |
| 3 | 6135831 | Serum human placental lactogen (hPL) and human chorionic gonadotropin (hCG) were assayed and fetal crown-rump length (CRL) was determined by sonar in three groups of pregnant women--35 with uncomplicated pregnancies, 13 with insulin-dependent diabetes mellitus, and 21 who represented a general pregnancy population. |
| 4 | 6378262 | Levels of human placental lactogen (HPL) were significantly elevated in B-noRx patients compared to PC and A and were lowered to levels comparable to normal in insulin-treated B patients. |
| 5 | 8372111 | In two experiments using 210 rats, bST and a similar hormone, bovine placental lactogen (bPL), both caused a small (14 to 27%) but statistically significant reduction in circulating adipsin protein. |
| 6 | 8238332 | We have previously shown that in normal pregnancy, a specific placental GH variant, rather than human placental lactogen (hPL), substitutes for pituitary GH in the regulation of maternal IGF-I. |
| 7 | 10619404 | The human growth hormone/chorionic somatomammotropin (hGH/CS) family consists of five genes, one of which (GH-N) is expressed efficiently in pituitary while the other four (CS-A, B, L, and hGH-V) are expressed in placenta and represent ultimate placental differentiation markers. |
| 8 | 16380478 | In contrast, p21(cip) was uniquely, dramatically, and reproducibly upregulated in placental lactogen and HGF islets. p21(cip) was also present in, and upregulated in, proliferating human islets, localizing specifically in beta-cells and translocating to the nucleus on mitogenic stimulation. |
| 9 | 16380478 | Homozygous p21(cip) loss releases islets from growth inhibition, markedly enhancing proliferation in response to HGF and placental lactogen. |