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Gene Information
Gene symbol: CXCL1
Gene name: chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
HGNC ID: 4602
Synonyms: SCYB1, GROa, MGSA-a, NAP-3
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | APLP2 | 1 hits |
| 2 | CXCL2 | 1 hits |
| 3 | CXCL3 | 1 hits |
| 4 | IAPP | 1 hits |
| 5 | PPARG | 1 hits |
| 6 | TLR2 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 18661119 | Prominently upregulated were chemokine C-X-C motif ligand 1 (CXCL1), CXCL2 and CXCL3 belonging to the CXC family of chemokines related to IL-8. |
| 2 | 19417127 | Furthermore, PPARgamma activation by rosiglitazone strongly suppresses cytokine-induced transcript levels of the NF-kappaB-dependent genes intracellular adhesion molecule 1 (ICAM-1) and CXCL1 (KC), the murine homolog of IL-8, in myotubes. |
| 3 | 21813778 | Early aggregates of hIAPP, but not nonamyloidogenic rodent islet amyloid polypeptide, caused release of CCL2 and CXCL1 by islets and induced secretion of TNF-?, IL-1?, IL-1?, CCL2, CCL3, CXCL1, CXCL2, and CXCL10 by C57BL/6 bone marrow-derived macrophages. hIAPP-induced TNF-? secretion was markedly diminished in MyD88-, but not TLR2- or TLR4-deficient macrophages, and in cells treated with the IL-1R antagonist (IL-1Ra) anakinra. |