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Gene Information
Gene symbol: CYP2C9
Gene name: cytochrome P450, family 2, subfamily C, polypeptide 9
HGNC ID: 2623
Synonyms: P450IIC9
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CYP2D6 | 1 hits |
| 2 | F7 | 1 hits |
| 3 | STN | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 17456829 | The importance of CYP2C9 and VKORC1 to patient-specific dose of warfarin has been confirmed, while polymorphisms of gamma carboxylase, factor VII and Apo E genes did not substantially contribute to predictive models for stable warfarin dose. |
| 2 | 20207952 | There were no differences for patients with variants of CYP2C9, CYP2C19, or SLCO1B1 in comparison with their respective wild types, nor were differential effects on statin response seen for patients with the most common genotypes for CYP3A5 and BCRP (n=415; odds ratio: 1.207; 95% CI: 0.768, 1.899; P=0.415). |
| 3 | 21276781 | While none of the OS components showed significant inhibition on CYP2C9, eupatorin strongly and uncompetitively inhibited CYP2D6 activity with a K(i) value of 10.2?M. |