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Gene Information
Gene symbol: DDIT4
Gene name: DNA-damage-inducible transcript 4
HGNC ID: 24944
Synonyms: RTP801, FLJ20500, REDD-1, REDD1, Dig2
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | HIF1A | 1 hits |
| 2 | INS | 1 hits |
| 3 | TP53 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 19996311 | However, the regulation of REDD1 expression in response to insulin remains unknown. |
| 2 | 19996311 | In the present study, we demonstrate that in murine and in human adipocytes, insulin stimulates REDD1 expression. |
| 3 | 19996311 | Moreover, using echinomycin, a hypoxia-inducible factor 1 (HIF-1) inhibitor, and HIF-1alpha small interfering RNA, we demonstrate that insulin stimulates REDD1 expression only through the transcription factor HIF-1. |
| 4 | 19996311 | In conclusion, our study shows that insulin stimulates REDD1 expression in adipocytes. |
| 5 | 21540236 | We show that metformin increases REDD1 expression in a p53-dependent manner. |