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Gene Information
Gene symbol: DLK1
Gene name: delta-like 1 homolog (Drosophila)
HGNC ID: 2907
Synonyms: FA1, pG2, Pref-1, ZOG, Delta1
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ADIPOQ | 1 hits |
| 2 | BMP7 | 1 hits |
| 3 | INS | 1 hits |
| 4 | NDN | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 18835937 | Preadipocyte factor-1 (Pref-1) is a secreted protein that inhibits adipocyte differentiation, both in vitro and in vivo. |
| 2 | 18835937 | In this study, we have investigated the effects of Pref-1 overexpression on whole-body glucose homeostasis and its contribution to the development of insulin resistance. |
| 3 | 15895078 | Necdin is also markedly increased in Irs knockout cells that cannot differentiate, and knockdown of necdin restores brown adipogenesis with downregulation of Pref-1 and Wnt10a expression. |
| 4 | 20584981 | The high level of adipogenic inhibitor preadipocyte factor 1 (Pref-1) in IRS-1-null cells was markedly reduced by 3 days of BMP7 treatment, and analysis of the 1.3-kb pref-1 promoter revealed 9 putative Smad binding elements (SBEs), suggesting that BMP7 could directly suppress Pref-1 expression, thereby allowing the initiation of the adipogenic program. |