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Gene Information
Gene symbol: DNMT3A
Gene name: DNA (cytosine-5-)-methyltransferase 3 alpha
HGNC ID: 2978
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | APOB | 1 hits |
| 2 | H19 | 1 hits |
| 3 | IGF2 | 1 hits |
| 4 | IGF2R | 1 hits |
| 5 | MYCN | 1 hits |
| 6 | PPARG | 1 hits |
| 7 | PPARGC1A | 1 hits |
| 8 | SCD | 1 hits |
| 9 | UCP3 | 1 hits |
| 10 | ZMPSTE24 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 21047779 | Here, we demonstrate that deletion of both Gsk-3? and Gsk-3? in mouse embryonic stem cells results in reduced expression of the de novo DNA methyltransferase Dnmt3a2, causing misexpression of the imprinted genes Igf2, H19, and Igf2r and hypomethylation of their corresponding imprinted control regions. |
| 2 | 21047779 | Finally, we find that N-Myc is a potent Gsk-3-dependent regulator of Dnmt3a2 expression. |
| 3 | 19680556 | We re-sequenced all exons, intron-exon boundaries and selected conserved non-coding sequences of candidate genes involved in aging-related processes, including dietary restriction (PPARG, PPARGC1A, SIRT1, SIRT3, UCP2, UCP3), metabolism (IGF1R, APOB, SCD), autophagy (BECN1, FRAP1), stem cell activation (NOTCH1, DLL1), tumor suppression (TP53, CDKN2A, ING1), DNA methylation (TRDMT1, DNMT3A, DNMT3B) Progeria syndromes (LMNA, ZMPSTE24, KL) and stress response (CRYAB, HSPB2). |