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Gene Information
Gene symbol: EIF2A
Gene name: eukaryotic translation initiation factor 2A, 65kDa
HGNC ID: 3254
Synonyms: EIF-2A
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | COMP | 1 hits |
| 2 | HSPA5 | 1 hits |
| 3 | INS | 1 hits |
| 4 | PTPN1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 16246168 | Mice devoid of the eIF2 kinase GCN2 [general control non-derepressible-2 or EIF2AK4 (eIF2alpha kinase 4)] show sensitivity to nutritional deficiencies and aberrant eating behaviours, and deletion of PEK [pancreatic eIF2alpha kinase or PERK (RNA-dependent protein kinase-like endoplasmic reticulum kinase) or EIF2AK3] leads to neonatal insulin-dependent diabetes, epiphyseal dysplasia and hepatic and renal complications. |
| 2 | 19066313 | Specifically, glucose-regulated protein 78 (Grp78) and spliced X-box binding protein-1 (sXBP-1) mRNA levels were reduced, as were phosphorylated elongation initiation factor 2alpha (eIF2alpha) and stress kinase c-Jun NH2-terminal kinase 1 (JNK1) (all P values <0.05). |
| 3 | 19074988 | Liver-specific PTP1B deletion also protects against high-fat diet-induced endoplasmic reticulum stress response in vivo, as evidenced by decreased phosphorylation of p38MAPK, JNK, PERK, and eIF2alpha and lower expression of the transcription factors C/EBP homologous protein and spliced X box-binding protein 1. |