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Gene Information
Gene symbol: ELOVL5
Gene name: ELOVL fatty acid elongase 5
HGNC ID: 21308
Synonyms: HELO1, dJ483K16.1
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | AKT1 | 1 hits |
| 2 | LEP | 1 hits |
| 3 | MLX | 1 hits |
| 4 | PPP2R4 | 1 hits |
| 5 | SREBF1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 16790840 | In leptin-deficient obese mice (Lep(ob/ob)), increased SREBP-1 and MLX nuclear content correlated with the induction of Elovl-5, Elovl-6, and Delta(9)D expression and the massive accumulation of monounsaturated fatty acids (18:1,n-7 and 18:1,n-9) in neutral lipids. |
| 2 | 21178610 | Elovl5 activity regulates hepatic C20-22 PUFA content, signaling pathways (Akt and PP2A) and transcription factors (SREBP-1, PPAR?, FoxO1 and PGC1?) that control fatty acid synthesis and gluconeogenesis. |