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Gene Information
Gene symbol: ELOVL6
Gene name: ELOVL fatty acid elongase 6
HGNC ID: 15829
Synonyms: FLJ23378, MGC5487, LCE
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | AKT1 | 1 hits |
| 2 | LEP | 1 hits |
| 3 | MLX | 1 hits |
| 4 | SREBF1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 16790840 | Increased nuclear sterol-regulatory element binding protein-1 (SREBP-1) correlated with enhanced expression of Elovl-6, Delta(5)D, Delta(6)D, and Delta(9)D. |
| 2 | 16790840 | Suppression of Elovl-6 and Delta(9)D expression in livers of streptozotocin-induced diabetic rats and high fat-fed glucose-intolerant mice correlated with low levels of nuclear SREBP-1. |
| 3 | 16790840 | In leptin-deficient obese mice (Lep(ob/ob)), increased SREBP-1 and MLX nuclear content correlated with the induction of Elovl-5, Elovl-6, and Delta(9)D expression and the massive accumulation of monounsaturated fatty acids (18:1,n-7 and 18:1,n-9) in neutral lipids. |
| 4 | 19259639 | Protection against diet-induced insulin resistance in Elovl6 (-/-) mice is partially due to restoration of hepatic insulin receptor substrate-2 and suppression of hepatic protein kinase C epsilon, resulting in restoration of Akt phosphorylation. |