- About
- Home
- Introduction
- Statistics
- Programs
- Dignet
- Gene
- GenePair
- Help & Docs
- Documents
- Help
- FAQs
- Links
- Acknowledge
- Disclaimer
- Contact Us
Gene Information
Gene symbol: ERBB3
Gene name: v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
HGNC ID: 3431
Synonyms: HER3
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ERBB2 | 1 hits |
| 2 | INS | 1 hits |
| 3 | PI3 | 1 hits |
| 4 | PIK3R1 | 1 hits |
| 5 | RPS6KB1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 9815939 | Four of six pancreatic cancer cell lines exhibited the 6.2-kb erbB-3 mRNA transcript, and all four cell lines coexpressed the epidermal growth factor receptor and erbB-2. |
| 2 | 9388271 | Following PMA-induced tyrosine phosphorylation, ErbB2 and ErbB3 were able to associate with the SH2 domains of several signaling proteins including the p85alpha subunit of phosphatidylinositol 3-kinase, Syp, and Grb2. |
| 3 | 9388272 | Prolonged insulin treatment resulted in decreased expression of both ErbB2 and ErbB3. |
| 4 | 9389501 | Insulin inhibits the increase in heregulin beta1 binding, as well as the increase in ErbB3 messenger RNA and protein. |
| 5 | 9389501 | Using chemical activators or antagonists, we sought to identify the signaling pathways that link insulin to ErbB3 expression. |
| 6 | 9389501 | The PI-3 kinase inhibitors, wortmannin and LY294002, completely blocked the inhibition of ErbB3 protein expression by insulin, suggesting a role for PI-3 kinase in the regulation of this growth factor receptor. |
| 7 | 9389501 | Rapamycin, an inhibitor of p70 S6 kinase, an enzyme downstream of PI-3 kinase, failed to block the effect of insulin on ErbB3 expression. |