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Gene Information
Gene symbol: ERN1
Gene name: endoplasmic reticulum to nucleus signaling 1
HGNC ID: 3449
Synonyms: IRE1, IRE1P
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | EIF2AK3 | 1 hits |
| 2 | JUN | 1 hits |
| 3 | PRKAA1 | 1 hits |
| 4 | WFS1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 16195229 | The expression of WFS1 is regulated by inositol requiring 1 and PKR-like ER kinase, central regulators of the unfolded protein response. |
| 2 | 20922715 | All three regulate portions of the transcriptional unfolded protein response, while PERK also attenuates protein synthesis during ER stress and IRE1 interacts directly with the c-Jun amino-terminal kinase stress kinase pathway. |
| 3 | 21896783 | The endoribonuclease activity of IRE1 appears to be required for AMPK activation in response to nitric oxide. |
| 4 | 21896783 | In addition to nitric oxide, stimulation of IRE1 endoribonuclease activity with the flavonol quercetin leads to IRE1-dependent AMPK activation. |