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Gene Information

Gene symbol: FGF10

Gene name: fibroblast growth factor 10

HGNC ID: 3666

Related Genes

# Gene Symbol Number of hits
1 CTNNB1 1 hits
2 FGF8 1 hits
3 FGFR2 1 hits
4 FOXA2 1 hits
5 NOTCH1 1 hits
6 PDX1 1 hits

Related Sentences

# PMID Sentence
1 9435295 Consistent with this defect, the expression of Fgf8, an apical ectodermal factor, is absent in the mutant presumptive limb ectoderm, and the expression of Fgf10, a mesenchymally expressed limb bud initiator, is down regulated in the underlying mesoderm.
2 9435295 These findings provide direct genetic evidence that FGF/FGFR2 signals are absolutely required for vertebrate limb induction and that an FGFR2 signal is essential for the reciprocal regulation loop between FGF8 and FGF10 during limb induction.
3 16611688 Robust stabilization of beta-catenin during early organogenesis drives changes in hedgehog and Fgf10 signaling and induces a loss of Pdx1 expression in early pancreatic progenitor cells.
4 20206178 During early stages of development, exposure of cells to noggin and retinoid acid, followed by FGF10, generated pancreatic cells (PDX1+; 50%-80%) that coexpressed FOXA2, HNF6, and SOX9.
5 14651921 The FGF10-positive pancreatic cells expressed Notch1 and Notch2, the Notch-ligand genes Jagged1 and Jagged2, as well as the Notch target gene Hes1.