Ignet

Gene Information

Gene symbol: FGF2

Gene name: fibroblast growth factor 2 (basic)

HGNC ID: 3676

Related Genes

#	Gene Symbol	Number of hits
1	ANXA5	1 hits
2	ATF4	1 hits
3	CYP19A1	1 hits
4	DBI	1 hits
5	EGF	1 hits
6	FGF7	1 hits
7	FOXA2	1 hits
8	GDF15	1 hits
9	INS	1 hits
10	KIT	1 hits
11	MCM8	1 hits
12	NEUROD1	1 hits
13	NOS3	1 hits
14	ONECUT1	1 hits
15	PAX6	1 hits
16	POU5F1	1 hits
17	PRKCA	1 hits
18	PSMD9	1 hits
19	PTHLH	1 hits

Related Sentences

#	PMID	Sentence
1	1671798	Although basic fibroblast growth factor (1-100 ng/ml), acidic fibroblast growth factor (1 ng/ml), epidermal growth factor (1 ng/ml), platelet-derived growth factor (1 ng/ml), tumor necrosis factor (1 ng/ml), and transforming growth factor-beta 1 (1 ng/ml) have no effect on basal aromatase activity in human skin fibroblasts, all of these growth factors inhibited the ability of dibutyryladenosine 3',5'-cyclic monophosphate to stimulate aromatase activity.
2	1900153	We have further characterized the protein kinase C (PK-C) dependent phosphorylation of basic fibroblast growth factor (FGF).
3	8425916	Treatment of Swiss 3T3 fibroblasts with basic fibroblast growth factor (bFGF) lead to a rapid reduction in epidermal growth factor (EGF) binding and a slower inhibition of EGF receptor autophosphorylation.
4	10643294	AGEs and basic fibroblast growth factor (bFGF) induced expression of KDR in REC, and a transcription factor Sp 1 was involved in this process.
5	11181569	Consistent with the in vivo observations, FGF2 inhibited bone growth in culture and induced downregulation of IHH and PTHrP receptor gene expression.
6	16079311	We conclude that physiological glucose concentrations are suitable for the culturing of EBs, that the addition of FGF2 enhances the temporal expression of genes including POU5F1, nestin, FOXA2, ONECUT1, NEUROD1, PAX6, and insulin, and that EBs can be cultured in vitro for long periods, allowing for further examination of developmental processes.
7	16433046	Vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), transforming growth factor-beta1 (TGF-beta1), endothelin-1 (ET-1) and soluble c-kit ligand (sKL) are cytokines involved in embryogenesis.
8	17109637	Taken together these data strongly suggest that FGF1 and FGF2 induce proliferation of pancreatic epithelial cells during the early post-natal period whereas FGF7 is not strictly specific for pancreatic cell proliferation.
9	19759273	Chronic high-glucose-based PDF exposure resulted in increased vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) expression, accumulation of advanced glycation end-products (AGEs), and up-regulation of the receptor for AGE (RAGE), which were ameliorated in the icodextrin-based PDF group.
10	21249158	In an independent experiment, insulin replacement therapy normalized the expression of some proteins (Dbi, Anxa5) while other proteins (Cp, Cryba3, Lgals3, Stat3) were only partially normalized and Fgf2 and Crybb2 expression remained elevated.
11	21143620	These beneficial effects of metformin were associated with increased AMPK and eNOS phosphorylation, as well as reductions in insulin, TGF-?1, basic fibroblast growth factor and tumour necrosis factor-? levels in the circulation and/or myocardium. 4.
12	17270172	Our results suggest that quiescence of small cells correlates with up-regulation of Cdk inhibitors p27(Kip1), p16(INK4a) and p21(CIP1), PTEN, Hep27 and Foxo1a and with down-regulation of c-Myc and the receptors for EGF, FGF2 and HGF.
13	20306012	ATF4 is induced in aortic smooth muscle cells by fibroblast growth factor 2 and in the intact vessel wall following balloon angioplasty.
14	21740847	Metformin also increased phosphorylation of AMPK and eNOS, and reduced the expression of TGF-?1, basic fibroblast growth factor (bFGF), and tumor necrosis factor (TNF)-?.