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Gene Information
Gene symbol: FGFR4
Gene name: fibroblast growth factor receptor 4
HGNC ID: 3691
Synonyms: JTK2, CD334
Related Genes
Related Sentences
# |
PMID |
Sentence |
1 |
19237543
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The bile acid receptor FXR (farnesoid X receptor) activates expression of fibroblast growth factor (FGF) 15 in the intestine, which acts through hepatic FGFR4 to suppress cholesterol-7alpha hydroxylase (CYP7A1) and limit bile acid production.
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2 |
19346330
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In the intestine, FXR induces an intestinal hormone, fibroblast growth factor 15 (FGF15; or FGF19 in human), which activates hepatic FGF receptor 4 (FGFR4) signaling to inhibit bile acid synthesis.
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