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Gene Information
Gene symbol: FKBP1A
Gene name: FK506 binding protein 1A, 12kDa
HGNC ID: 3711
Synonyms: FKBP-12, FKBP12, PKC12, PPIASE, FKBP12C
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | BLVRB | 1 hits |
| 2 | CAT | 1 hits |
| 3 | GNAQ | 1 hits |
| 4 | HSPB1 | 1 hits |
| 5 | HSPD1 | 1 hits |
| 6 | INS | 1 hits |
| 7 | NOS2A | 1 hits |
| 8 | SOD1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 19805579 | FK506 binding protein 12.6 kDa (FKBP12.6), a protein that regulates ryanodine Ca(2+) release channels, may act as an important regulator of insulin secretion. |
| 2 | 20372981 | Thus, based on the present study we suggest a signaling pathway via the G(q)-proteins, G(alpha)(11) and G(alpha)(q), that could link increased neurohumoral stimulation in diabetes with defective RyR2 channel function by regulating protein expression of FKBP12.6, annexin A7, and sorcin. |
| 3 | 20360867 | Using proteomic and ultrastructural approaches, multiple alterations in the expression of proteins involved in oxidative stress (catalase, superoxide dismutase 1, Hsp27, Hsp60, ATP synthase delta chain, and flavin reductase), aerobic and anaerobic glycolysis (ACBP, pyruvate kinase muscle isozyme, and phosphoglycerate kinase 1), and intracellular signaling (stratifin-14-3-3, S100-calcyclin, cathepsin, and PPI rotamase) as well as endothelial vascular abnormalities were identified in T1D and T1D+ESRD patients. |
| 4 | 21441944 | Cardiac dysfunction and myocardial hypertrophy of the diabetic rats were associated with increased mRNA and protein expression of iNOS, OBRb, and PKC?, while expression of CASQ2, SERCA2a, and FKBP12.6 was significantly down-regulated. |