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Gene Information
Gene symbol: FLT3
Gene name: fms-related tyrosine kinase 3
HGNC ID: 3765
Synonyms: STK1, FLK2, CD135
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD34 | 1 hits |
| 2 | CSF1R | 1 hits |
| 3 | CXCL10 | 1 hits |
| 4 | IFNG | 1 hits |
| 5 | IL2 | 1 hits |
| 6 | IL8 | 1 hits |
| 7 | IL9 | 1 hits |
| 8 | KITLG | 1 hits |
| 9 | THPO | 1 hits |
| 10 | VEGFA | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 21262836 | In this study, we show that IL-2 inhibits the development of both pDCs and cDCs from bone marrow cells under flt3L stimulation, by acting on lineage(-) flt3(+) precursors. |
| 2 | 21723532 | We measured significant alterations in the vitreous concentrations of 9 cytokines-eotaxin, Flt-3 ligand, growth-related oncogene (GRO), interleukin (IL)-6, IL-8, IL-9, IFN-inducible protein-10 (IP-10), macrophage-derived cytokine (MDC), and vascular endothelial growth factor (VEGF)-in advanced proliferative diabetic retinopathy, and found that oxygen tension at the posterior pole was directly correlated with vitreous VEGF concentration. |
| 3 | 21544097 | Single 24?h transduction of human CD34(+) cells with human immunodeficiency virus type 1 (HIV1)-based lentiviral vectors in media containing stem cell factor (SCF), FMS-like tyrosine kinase 3 (FLT3) ligand, thrombopoietin (each 100?ng?ml(-1)) and 10% fetal bovine serum was compared with various cytokine conditions during ex vivo culture and assayed using humanized xenograft mice for 6 months after transplantation. |
| 4 | 21544097 | In summary, 24?h prestimulation followed by single 24-h lentiviral transduction in serum-free media with SCF, FLT3 ligand and thrombopoietin yields high transduction efficiency to engrafting human CD34(+) cells, and is applicable in human clinical gene therapy trials. |