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Gene Information

Gene symbol: FSHB

Gene name: follicle stimulating hormone, beta polypeptide

HGNC ID: 3964

Related Genes

# Gene Symbol Number of hits
1 ADCYAP1 1 hits
2 EGR1 1 hits
3 FOS 1 hits
4 GNRH1 1 hits
5 INHBE 1 hits
6 PPARG 1 hits
7 PRL 1 hits
8 TRH 1 hits

Related Sentences

# PMID Sentence
1 707005 Failure of growth hormone (hGH), cortisol and prolactin to respond to insulin induced hypoglycaemia (0.1 U/kg), of luteinizing hormone (LH) and follicle stimulating hormone (FSH) to respond to gonadotrophin releasing hormone (GnRH, 100 microgram) and of thyrotrophin (TSH) and prolactin to increase after thyrotrophin releasing hormone (TRH, 500 microgram), confirmed the diagnosis of panhypopituitarism.
2 8472873 Follistatin was originally identified as a specific inhibitor of follicle stimulating hormone secretion and later characterized as a binding protein for activin.
3 21076077 Depletion of PPARG using a lentivirally encoded short hairpin RNA abolishes the effect of rosiglitazone to suppress activation of JNKs and induction of the transcription factors EGR1 and FOS as well as the gonadotropin genes Lhb and Fshb.
4 21191111 PACAP increases alpha-subunit (Cga) and Lhb mRNAs, and it stimulates the transcription of follistatin (Fst) that, in turn, restrains activin signaling to repress Fshb and gonadotropin-releasing hormone-receptor (Gnrhr) expression as well as other activin-responsive genes.
5 21191111 At birth, pituitary PACAP declines and pituitary follistatin levels decrease, which together with increased gonadotropin-releasing hormone secretion allow Gnrhr and Fshb to increase and facilitate activation of the newborn gonads.