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Gene Information

Gene symbol: GATA1

Gene name: GATA binding protein 1 (globin transcription factor 1)

HGNC ID: 4170

Synonyms: ERYF1, NFE1, GATA-1

Related Genes

#	Gene Symbol	Number of hits
1	EPOR	1 hits
2	HBA2	1 hits
3	SP1	1 hits

Related Sentences

#	PMID	Sentence
1	1990287	We show that expression in fibroblasts of a single cDNA, encoding the erythroid DNA-binding protein Eryf1 (GF-1, NF-E1), very efficiently activates transcription of a chicken alpha-globin promoter, trans-Activation in these cells occurred when Eryf1 bound to a single site within a minimal globin promoter.
2	7659529	By increasing GATA-1 levels via co-transfection, we were able to transactivate the hEpoR promoter in K562 cells and non-erythroid cells, but not in the highly active OCIM1 cells, although GATA-1 mRNA levels were comparable in OCIM1 and K562.
3	7659529	Rather, hEpoR transcription activity depends on coordination between Sp1 and GATA-1 with other cell-specific factors, including possibly other Sp1-like binding proteins, to provide high level, tissue-specific expression.
4	8810316	In vitro assays demonstrated that: (a) the TATA motif at -30 bound GATA-1, (b) Sp1 bound to an element centered at -54, and (c) both Sp1 and another factor, designated CACCC (which appears related to erythroid Krüppel-like factor, EKLF) bound in the -120 to -128 region.