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Gene Information
Gene symbol: GATA3
Gene name: GATA binding protein 3
HGNC ID: 4172
Synonyms: HDR
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | GCM2 | 1 hits |
| 2 | HPT | 1 hits |
| 3 | HSPD1 | 1 hits |
| 4 | IFNG | 1 hits |
| 5 | NFATC2 | 1 hits |
| 6 | NFKB1 | 1 hits |
| 7 | TBX21 | 1 hits |
| 8 | TNF | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 14985365 | The hypoparathyroidism, deafness, and renal dysplasia (HDR) syndrome is an autosomal dominant disorder caused by mutations of the dual zinc finger transcription factor, GATA3. |
| 2 | 15749853 | We now report that HSP60 in vitro differentially modulates the expression of Th1/Th2 transcription factors in human T cells: HSP60 down-regulates T-bet, NF-kappaB, and NFATp and up-regulates GATA-3, leading to decreased secretion of TNF-alpha and IFN-gamma and enhanced secretion of IL-10. |
| 3 | 20484821 | Heterozygous mutations of GATA3, which encodes a dual zinc-finger transcription factor, cause hypoparathyroidism with sensorineural deafness and renal dysplasia. |
| 4 | 20484821 | At E11.5, Gata3+/- embryos had smaller parathyroid-thymus primordia with fewer cells expressing the parathyroid-specific gene glial cells missing 2 (Gcm2), the homolog of human GCMB. |