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Gene Information

Gene symbol: GLUL

Gene name: glutamate-ammonia ligase

HGNC ID: 4341

Related Genes

# Gene Symbol Number of hits
1 GLS 1 hits
2 NEUROD1 1 hits
3 SST 1 hits

Related Sentences

# PMID Sentence
1 1463765 In gastrocnemius muscle, glutamine synthetase activity (Vmax) was unaltered by diabetes (approx. 235 nmol/min per g) but glutaminase Vmax increased from 146 +/- 29 to 401 +/- 94 nmol/min per g; substrate Km values of neither enzyme were affected by diabetes.
2 10736366 Experiments in vivo suggest that changes in net hepatic glutamine balance are due predominantly to regulation of glutaminase activity, with the flux through glutamine synthetase being relatively constant.
3 11934540 Control of hepatic glutamine metabolism occurs almost exclusively through changes in the activity of glutaminase, with no change in glutamine synthetase flux.
4 20536387 Glul, Lgmn and Reg3? change the expression level of islet marker genes, where NEUROD, NKX2.2, PAX4 and PAX6 are up-regulated and somatostatin is down-regulated.