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Gene Information
Gene symbol: GLUL
Gene name: glutamate-ammonia ligase
HGNC ID: 4341
Related Genes
Related Sentences
# |
PMID |
Sentence |
1 |
1463765
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In gastrocnemius muscle, glutamine synthetase activity (Vmax) was unaltered by diabetes (approx. 235 nmol/min per g) but glutaminase Vmax increased from 146 +/- 29 to 401 +/- 94 nmol/min per g; substrate Km values of neither enzyme were affected by diabetes.
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2 |
10736366
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Experiments in vivo suggest that changes in net hepatic glutamine balance are due predominantly to regulation of glutaminase activity, with the flux through glutamine synthetase being relatively constant.
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3 |
11934540
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Control of hepatic glutamine metabolism occurs almost exclusively through changes in the activity of glutaminase, with no change in glutamine synthetase flux.
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4 |
20536387
|
Glul, Lgmn and Reg3? change the expression level of islet marker genes, where NEUROD, NKX2.2, PAX4 and PAX6 are up-regulated and somatostatin is down-regulated.
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