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Gene Information
Gene symbol: GPR120
Gene name: G protein-coupled receptor 120
HGNC ID: 19061
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CCK | 1 hits |
| 2 | FFAR1 | 1 hits |
| 3 | GCG | 1 hits |
| 4 | INS | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 20471368 | The newly discovered G protein-coupled receptor GPR120 has recently been shown to stimulate secretion of the gut hormones glucagon-like peptide-1 and cholecystokinin upon binding of free fatty acids, thrusting it to the forefront of drug discovery efforts for treatment of type 2 diabetes as well as satiety and obesity. |
| 2 | 19817784 | GPR120 is expressed in L-cells and was also shown to mediate FA-stimulated GLP-1 release. |
| 3 | 21663979 | We have recently shown that GPR120 acts as a physiological receptor of ?3 fatty acids in macrophages and adipocytes, which mediate potent anti-inflammatory and insulin sensitizing effects. |
| 4 | 21618241 | FFAR1 facilitates glucose-stimulated insulin secretion from pancreatic ?-cells, whereas GPR120 regulates the secretion of glucagon-like peptide-1 in the intestine, as well as insulin sensitivity in macrophages. |