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Gene Information
Gene symbol: HDAC9
Gene name: histone deacetylase 9
HGNC ID: 14065
Synonyms: KIAA0744, HDAC, MITR, HD7, HDAC7B
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | BCL6 | 1 hits |
| 2 | EGFR | 1 hits |
| 3 | HDAC2 | 1 hits |
| 4 | HES1 | 1 hits |
| 5 | IFNGR2 | 1 hits |
| 6 | INS | 1 hits |
| 7 | JMJD2C | 1 hits |
| 8 | NFKB1 | 1 hits |
| 9 | RPS27A | 1 hits |
| 10 | RUNX1T1 | 1 hits |
| 11 | SLC2A4 | 1 hits |
| 12 | TGFA | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 12482846 | Here, we show that blockade of corepressor histone de-acetylase (HDAC) activity reverses the differential inhibitory effect of SERMs upon AF-1 activity in MCF-7 cells. |
| 2 | 15156183 | The list of corepressors capable of binding ETO includes histone deacetylases (HDACs) and components of distinct HDAC core complexes. |
| 3 | 18762022 | The GR directly interferes with Hes1 promoter activity, triggering the recruitment of histone deacetylase (HDAC) activities to the Hes1 gene. |
| 4 | 20175943 | Also, EGCG decreased NF-kappaB activity and increased HDAC activity and HDAC-2 expression in Tregs (P < 0.05) in both groups. |
| 5 | 19793100 | The HDACs are also regulated by ubiquitin-mediated proteasomal degradation, although the exact mediators of this process have not been identified. 5. |
| 6 | 21047791 | In this paper, we have tested the hypothesis that differentiation-dependent GLUT4 gene expression in 3T3-L1 adipocytes is dependent on the nuclear concentration of a class II histone deacetylase (HDAC) protein, HDAC5. |
| 7 | 21047791 | Together, our data indicate that class II HDAC expression is the major regulatory mechanism for inhibiting GLUT4 expression in the predifferentiated state. |
| 8 | 19553350 | This study examined the effect of HDAC inhibition on renal fibrosis induced by diabetes or transforming growth factor (TGF)-beta1 and determined the role of reactive oxygen species (ROS) as mediators of HDAC activation. |
| 9 | 19553350 | Among the six HDACs tested (HDAC-1 through -5 and HDAC-8), HDAC-2 activity significantly increased in the kidneys of STZ-induced diabetic rats and db/db mice and TGF-beta1-treated NRK52-E cells. |
| 10 | 21274504 | In addition to improving insulin resistance and preventing ?-cell inflammatory damage, there is evidence of genetic association between diabetes and histone deacetylases (HDACs); and HDAC inhibitors (HDACi) promote ?-cell development, proliferation, differentiation and function and positively affect late diabetic microvascular complications. |
| 11 | 21637537 | Trichostatin A, a HDAC inhibitor, reduces the repressive effect of JMJD2C. |
| 12 | 21708950 | HDAC9 deficiency also resulted in increased GATA3 and roquin and decreased BCL6 gene expression. |
| 13 | 21389970 | Attenuating effects of HDAC inhibition, although multifactorial, are likely to be mediated in part through downregulation of the EGFR. |