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Gene Information
Gene symbol: HMGB1
Gene name: high mobility group box 1
HGNC ID: 4983
Synonyms: HMG3, SBP-1, DKFZp686A04236
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | APOE | 1 hits |
| 2 | INS | 1 hits |
| 3 | SRY | 1 hits |
| 4 | TLR2 | 1 hits |
| 5 | UCP1 | 1 hits |
| 6 | VEGFA | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 15469275 | We demonstrate the applicability of this approach to HMG-box proteins and contrast the results obtained for nonspecific DNA binding of the A-box of HMGB-1 (HMGB-1A) with sequence-specific DNA binding of the related SRY protein. |
| 2 | 18511846 | Both RAGE and RAGE ligands, including S100A8/A9, high mobility group box 1 (HMGB1), and the advanced glycation end product (AGE) carboxymethyllysine were increased in plaques from diabetic apoE(-/-) mice. |
| 3 | 20699433 | Insulin did not affect TNF-?, MCP-1, IL-6, LBP, resistin, and HMG-B1 increases induced by the LPS. |
| 4 | 20200317 | Furthermore, we observed that HMGB1 administration restored the blood flow recovery and capillary density in the ischemic muscle of diabetic mice, that this process was associated with the increased expression of vascular endothelial growth factor (VEGF), and that HMGB1-induced angiogenesis was significantly reduced by inhibiting VEGF activity. |
| 5 | 20809521 | Our results show that islet graft failure can be initiated by TLR2 and TLR4 signaling and suggest that HMGB1 is one likely early mediator. |
| 6 | 19833897 | High glucose increased RAGE, S100A8, S100A12, and HMGB1 expression, which was normalized by overexpression of UCP1, SOD2, or GLO1. |