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Gene Information
Gene symbol: HMGCR
Gene name: 3-hydroxy-3-methylglutaryl-CoA reductase
HGNC ID: 5006
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | APLP2 | 1 hits |
| 2 | COG2 | 1 hits |
| 3 | INS | 1 hits |
| 4 | TKT | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 19327767 | Variation in the HMGCR gene may influence component features of PCOS, including insulin resistance, SHBG, and free T. |
| 2 | 20450981 | Hmgcr and Mogat1 RNA expression levels were reduced in the livers and those of Tkt were increased in the kidney of BPS treated rats compared with those in untreated rats. |
| 3 | 18802019 | CONCLUSIONS: We identified variants in HMGCR that are associated with LDL-C across populations and affect alternative splicing of HMGCR exon13. |
| 4 | 21812109 | By 6 ?h, acrolein altered hepatic gene expression including Insig1, Insig2 and Hmgcr genes and stimulated an acute-phase response (APR) with up-regulation of serum amyloid A genes (Saa) and systemic hypoalbuminemia. |