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Gene Information
Gene symbol: HSD11B2
Gene name: hydroxysteroid (11-beta) dehydrogenase 2
HGNC ID: 5209
Synonyms: SDR9C3
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | HSD11B1 | 1 hits |
| 2 | NR3C1 | 1 hits |
| 3 | NR3C2 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 15241735 | As 9alpha-fluorination (such as in 9alpha-fluorocortisol) decreases oxidation by HSD2 and increases both GC and MC receptor transactivation, this modification leads to optimal, but non-selective transactivation of both receptors. |
| 2 | 21806804 | We measured maternal serum levels of corticosterone, and the placental basal and labyrinth zone expression of glucocorticoid receptor (NR3C1), 11-hydroxysteroid dehydrogenase B 1 (HSD11B-1) predominantly activates cortisone to cortisol and 11-dehydrocorticosterone (11-DHC) to corticosterone, although can sometimes drive the opposing (inactivating reaction), and HSD11B-2 (only inactivates and converts corticosterone to 11-DHC in rodents) in control and MUN rats at embryonic day 20 (E20). |