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Gene Information
Gene symbol: HSP90AA1
Gene name: heat shock protein 90kDa alpha (cytosolic), class A member 1
HGNC ID: 5253
Synonyms: Hsp89, Hsp90, FLJ31884, HSP90N
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CDC2 | 1 hits |
| 2 | HSPA1A | 1 hits |
| 3 | STAT3 | 1 hits |
| 4 | STUB1 | 1 hits |
| 5 | TPR | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 20043882 | Interestingly, as for the activation of S6K1, suppression of Cdk1 is involved in the stabilization of Akt protein by DEDD, since diminishment of Cdk1 in DEDD(-/-) cells via siRNA expression or treatment with a Cdk1-inhibitor, increases both Akt and Hsp90 protein levels. |
| 2 | 19506739 | Consistent with this model, Hsp90 has recently been shown to be a chaperone for Tah1p (TPR-containing protein associated with Hsp90) and Pih1p (protein interacting with Hsp90), which connect to the chromatin remodelling factor Rvb1p (RuvB-like protein 1)/Rvb2p in yeast [1]. |
| 3 | 20711301 | Hsp90 is the master regulator of the heat-shock response and its inhibition can up-regulate Hsp70. |
| 4 | 20885985 | Data further shows that MGO decreases the levels of the molecular chaperones Hsc70 and Hsp90 and leads to accumulation of CHIP-, Hsp40- and ubiquitin-containing aggregates. |
| 5 | 21617181 | Several steps in STAT3 activation require its association with heat shock protein 90 (Hsp90), which was prevented by GW501516 as revealed in immunoprecipitation studies. |