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Gene Information
Gene symbol: ICOS
Gene name: inducible T-cell co-stimulator
HGNC ID: 5351
Synonyms: AILIM, CD278
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD40 | 1 hits |
| 2 | IL2 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 16380473 | Using a fully allogeneic mouse model, we tested the effectiveness of the combined blockade of the CD40 ligand and the inducible costimulator (ICOS) on islet allograft survival and in the prevention of autoimmune diabetes in the NOD mouse. |
| 2 | 16380473 | Recipients treated with blocking monoclonal antibodies (mAbs) to ICOS and the CD40 ligand had significant prolongation of graft survival, with 26 of 28 functioning for >200 days. |
| 3 | 20679400 | Low-dose IL-2 increases the number of T reg cells in the pancreas and induces expression of T reg cell-associated proteins including Foxp3, CD25, CTLA-4, ICOS (inducible T cell costimulator), and GITR (glucocorticoid-induced TNF receptor) in these cells. |